During the Adult Years. Introduction Osteogenesis imperfecta (OI) is a genetic disorder characterized by bones that break easily, often from little or no apparent trauma. It is caused by a genetic defect that affects the body’s production of type I collagen, which is the major protein in connective tissue. The Adult Health Initiative: Working to Improve the Health and Well-being of Adults with Osteogenesis Imperfecta. The Adult Health Initiative is a multi-year effort sponsored by the OI Foundation. It is a series of research projects, publications, and outreach efforts to OI Adults and their Physicians.
Osteogenesis imperfecta (OI), also known as brittle bone disease, is a group of genetic disorders that mainly affect the bones. It results in bones that break easily. The severity may be mild to severe. Other symptoms may include a blue tinge to the whites of the eye, short height, loose joints, hearing loss, breathing problems and problems with the teeth.Causes: Genetic (autosomal dominant, new mutation). Osteogenesis imperfecta (OI) is a genetic disorder characterized by bones that break easily. OI is highly variable. Its signs and symptoms range from mild to severe. In addition to fractures (broken bones), people with OI sometimes have muscle weakness, loose joints (joint laxity), curvature of the spine (scoliosis), brittle teeth.
Feb 03, 2014 · A 42-year-old premenopausal woman with osteogenesis imperfecta presents to the metabolic bone clinic. She has a daughter with osteogenesis imperfecta who is seen regularly in a specialist pediatric clinic, but the patient herself hasn’t had Cited by: 15. Osteogenesis Imperfecta. Also known as “brittle bone disease,” osteogenesis imperfecta (OI) is a genetic disorder that causes weak bones that break easily in addition to other symptoms. There are several forms of OI, and although there is no cure, the symptoms of OI can be managed with a healthy lifestyle, medication, or surgery.
Osteogenesis imperfecta (OI) is a genetic disorder that causes a person's bones to break easily, often from little or no apparent trauma. OI is also called "brittle bone disease." OI varies in severity from person to person, ranging from a mild type to a severe type that causes death before or shortly after birth. Jan 14, 2016 · Osteogenesis imperfecta type IV (OI type IV) is a type of osteogenesis imperfecta, which refers to a group of conditions that affect the bones.OI type IV is the most variable form of the condition with symptoms ranging from moderately severe to so mild that it may be difficult to make the diagnosis.